Are the New Alzheimer's Drugs Really "Disease-Modifying"?

What the evidence supports about lecanemab and donanemab — and what it does not.

May 17 • Hussein Yassine

16

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6

What a New Study Gets Wrong About Fish Oil

And why association is not causation

May 10 • Hussein Yassine

13

3

Meet the Brain's Immune System — and Why It's the Next Big Bet Against Alzheimer's

A drug designed to supercharge the brain's immune cells just failed its biggest clinical test; but all is not lost.

May 4 • Hussein Yassine

13

4

3

April 2026

Use It or Lose It

How mental activity affects the risk of dementia

Apr 19 • Hussein Yassine

7

1

The Vascular Side of Alzheimer's: A New Hypothesis for Why the Brain Bleeds

A fresh Perspective on vascular inflammation in AD

Apr 12 • Hussein Yassine

13

3

3

What the World's Oldest Person Teaches Us About Inflammation and Longevity

No single diet, supplement, or habit made her 117.

Apr 5 • Hussein Yassine

3

March 2026

When Your Brain's Immune System Burns Out: A New Way to Think About Alzheimer's Disease

What if Alzheimer's isn't just about the buildup of toxic proteins — but about the immune cells that were supposed to clean them up, and why they…

Mar 30 • Hussein Yassine

14

3

4

Red Meat, APOE4, and the Limits of Observational Nutrition Science

Observational studies can drive you nuts!

Mar 23 • Hussein Yassine

15

8

3

The Amyloid Hypothesis of Alzheimer's Disease: What is Validated, What is Missed, and What Comes Next

One of the most debated hypotheses in modern medicine

Mar 15 • Hussein Yassine

11

12

3

Hormone Replacement Therapy, Brain Health, and APOE4

Understanding the benefits, risks, and unanswered questions surrounding hormone therapy and cognitive aging.

Mar 8 • Hussein Yassine

15

2

2

February 2026

To Statin or Not To Statin for Alzheimer's?

Why the best case for statins in APOE4 is vascular, not “Alzheimer’s treatment”

Feb 23 • Hussein Yassine

14

3

2

cPLA2 and the Synapse

New human data on an inflammatory enzyme linked to cognitive impairment in Alzheimer's disease

Feb 16 • Hussein Yassine

8

2