APOE4 and Traumatic Brain Injury

Understanding Risk and Recovery

Oct 12 • Hussein Yassine

6

1

1

Lithium Orotate, APOE4, and Alzheimer Prevention

Interesting biology, a possible “Goldilocks” effect, and a lot we still do not know

Oct 4 • Hussein Yassine

24

5

September 2026

Hearing Loss, APOE4, and Dementia

Could hearing loss be a second hit to a vulnerable brain?

Sep 20 • Hussein Yassine

6

5

2

Alcohol, APOE4, and the Brain

How much alcohol is too much with APOE4?

Sep 13 • Hussein Yassine

17

6

3

APOE4, Inflammation, and Cognitive Decline

Toward precision inflammation trials in Alzheimer disease

Sep 6 • Hussein Yassine

20

11

3

August 2026

Do Brain Games Prevent Dementia?

A reading into brain games, cognitive stimulation, and dementia prevention

Aug 30 • Hussein Yassine

8

1

GLP-1 Microdosing for Inflammation and Longevity?

What the Evidence Means for Lean APOE4 Carriers

Aug 23 • Hussein Yassine

13

6

3

Ceperognastat and the Limits of Tau Biomarker Translation

Tau PET tracks Alzheimer’s disease better than amyloid PET, but tracking disease is not the same as proving what will rescue the brain.

Aug 16 • Hussein Yassine

10

2

4

Why Aren’t We Giving APOE2 to APOE4 Carriers?

APOE2 may protect the aging brain, but it is not a simple genetic upgrade.

Aug 9 • Hussein Yassine

19

5

4

Protein Maxing Helps Muscle. But Does it Help Aging?

The Protein Longevity Paradox

Aug 1 • Hussein Yassine

10

10

1

July 2026

Exercise, Sitting, and APOE4

Why movement may matter most before symptoms begin — and what to do now.

Jul 26 • Hussein Yassine

28

5

8

P-tau217 and the Search for a Goldilocks Window in Alzheimer Prevention Trials

What a Major New Study Says About an Alzheimer’s Blood Test, and What It Doesn’t

Jul 21 • Hussein Yassine

8

4

2