Thanks for another great post! My 30,000 ft, I-know-enough-to-be-dangerous view has always been that AD has its roots in the brain's immune system. It just makes too much sense. The answers are there and those early failed trials still gave us valuable data. At my age, my best offense is a great defense to mitigate risk, but I'm super excited for the treatment options that will be available for the next generations.
Thanks for another great post! My 30,000 ft, I-know-enough-to-be-dangerous view has always been that AD has its roots in the brain's immune system. It just makes too much sense. The answers are there and those early failed trials still gave us valuable data. At my age, my best offense is a great defense to mitigate risk, but I'm super excited for the treatment options that will be available for the next generations.
What did you make of Rudy Tanzi’s group’s recent work showing female immunosuppression benefitted cognition but to do it in males worsened cognition?
I am not aware of these recent studies.
https://www.cell.com/neuron/fulltext/S0896-6273(26)00135-2